Editor's Cancer Comment on New Cancer Causing Agents:
Did you ever wonder if that yearly dental x-ray was safe?
Well those small x-ray exposures might be safe for some, but for
people like me who have a family history of cancer we need to reconsider
what is absolutely necessary.
Well, it's official! X-rays have been added as a cancer causing
agent!
The cancer epidemic has reach a point that even the US Government
has finally acknowledged publicly that so much of what we are exposed
to on a daily basis increases our exposure to environmental triggers
of cancer.
17 new cancer causing agents have been added.
For the first time ever, viruses are listed in the report:
- Hepatitis B virus
- Hepatitis C virus
- Certain human papillomaviruses
Other new listings include :
- Lead and lead compounds
- X-rays
- Compounds found in grilled meats
- Host of substances used in textile dyes, paints and inks
One of the most important statement in this release comes Dr. Kenneth
Olden
"Research shows that environmental factors
trigger
diseases like cancer, especially when someone has a family history
Don't despair knowledge is power.
Take comfort in knowing that making a few conscious choices about
what we expose ourselves to will significantly reduce our risk to
cancer causing agents.
read the full article below
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National Institute of Environmental Health Sciences (NIEHS)
FOR IMMEDIATE RELEASE
Monday, January 31, 2005
Research Triangle Park, N.C. The Department of Health and
Human Services released its Eleventh Edition of the Report on Carcinogens
today, adding seventeen substances to the growing list of cancer-causing
agents, bringing the total to 246.
For the first time ever, viruses are listed in the report:
- Hepatitis B virus
- Hepatitis C virus
- Certain human papillomaviruses
Other new listings include :
- Lead and lead compounds
- X-rays
- Compounds found in grilled meats
- Host of substances used in textile dyes, paints and inks
Among U.S. residents, 1 in 2 men and 1 in 3 women will develop
cancer at some point in their lifetimes.
Research shows that environmental factors trigger diseases like
cancer, especially when someone has a family history, said
Kenneth Olden, Ph.D., director of the National Institute of Environmental
Health Sciences and the National Toxicology Program, which prepared
the report for HHS.
The Report on Carcinogens, Eleventh Edition, referred to as the
RoC, lists cancer-causing agents in two categories
known to be human carcinogens and reasonably anticipated
to be human carcinogens.
The report now contains 58 known and 188 reasonably
anticipated listings. Federal law requires the Secretary of
the Department of Health and Human Services to publish the report
every two years.
Six substances have been added to the known category:
Hepatitis B virus (HBV) and hepatitis C virus (HCV) are viruses
that cause acute or chronic liver disease.
They are listed in the report as known human carcinogens
because studies in humans show that chronic hepatitis B and hepatitis
C infections cause liver cancer. Approximately one million United
States residents are chronically infected with HBV, which primarily
is transmitted through sexual contact (50%) and intravenous drug
use (15%).
HCV is the leading cause of liver disease in the United States
with more than three million people infected. The major risk factor
for hepatitis C infection is illegal intravenous drug use, which
accounts for 60 percent of acute infections in adults. The incidence
of both hepatitis B and hepatitis C infections is decreasing among
United States residents. A vaccine is available for preventing hepatitis
B infection but not hepatitis C infection. Infections can also be
prevented by screening blood supplies, and by reducing contact with
contaminated fluids in health care settings.
Human papillomaviruses (HPVs) are viruses that are sexually transmitted
and can infect genital and mucous membranes. Some of these genital
mucosal type HPVs are listed in the report as known human
carcinogens because studies show they cause cervical cancer
in women. Approximately 20 million people in the United States are
infected with genital HPVs, and 5.5 million new infections occur
each year. Most people infected do not have symptoms, but some develop
genital warts or cervical abnormalities.
X-radiation and gamma-radiation are listed in the report as known
human carcinogens because human studies show that exposure
to these kinds of radiation causes many types of cancer including
leukemia and cancers of the thyroid, breast and lung.
The risk of developing cancers due to these forms of ionizing
radiation depends to some extent on age at the time of exposure.
Childhood exposure is linked to an increased risk for leukemia and
thyroid cancer. Exposure during reproductive years increases the
risk for breast cancer, and exposure later in life increases risk
for lung cancer.
Exposure to X-radiation and gamma radiation has also been shown
to cause cancer of the salivary glands, stomach, colon, bladder,
ovaries, central nervous system and skin.
Of the total worldwide exposure to X-radiation and gamma-radiation,
55 percent is from low-dose medical diagnosis such as bone, chest
and dental X-rays, and 43 percent is from natural sources like radon.
Other sources, such as industry, scientific research, military
weapons testing, nuclear accidents and nuclear power generation,
account for about 2 percent.
Neutrons are also listed in the report as a known human carcinogen.
They cause genetic damage similar to that of X-radiation and gamma
radiation, and thus can cause the same cancers. Neutron radiation
is used less than other types of radiation in industry, medicine,
and research. The general population is exposed to neutrons primarily
from cosmic radiation that penetrates the earths atmosphere.
Eleven substances have been added to the reasonably anticipated
category:
Naphthalene is used as an intermediate in the synthesis of many
industrial chemicals, and has been used as an ingredient in some
moth repellants and toilet bowl deodorants. Naphthalene is listed
in the report as reasonably anticipated to be a human carcinogen,
based on inhalation studies in animals which showed it causes rare
nasal tumors in rats and benign lung tumors in female mice.
MeIQ, MeIQx, and PhIP are heterocyclic amine compounds formed when
meats and eggs are cooked or grilled at high temperatures. These
compounds are also found in cigarette smoke. They are listed in
the report as reasonably anticipated to be human carcinogens
because oral studies in animals showed they caused cancer in multiple
organs including the forestomach, colon, liver, oral cavity, mammary
gland, skin, and cecum. Several human studies suggest there is an
increased risk for breast and colorectal cancers related to consumption
of broiled or fried foods that may contain these or other similar
compounds.
MeIQ is 2-Amino-3, 4-dimethylimidazo [4,5-f]quinoline
MeIQx is 2-Amino-3, 8-dimethylimidazo [4,5-f]quinoxaline
PhIP is 2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine
Lead is used to make lead-acid storage batteries, ammunition, and
cable coverings. Lead compounds are used in paint, glass and ceramics,
fuel additives, and in some ethnic and ceremonial cosmetics. The
report lists lead and lead compounds as reasonably anticipated
to be human carcinogens because exposure to lead or lead compounds
is associated with a small increased risk for lung or stomach cancer
in humans, and cancer of the kidney, brain or lung in studies with
laboratory animals.
Cobalt Sulfate is used in electroplating, as coloring agents for
ceramics, and as drying agents in inks and paints. Cobalt sulfate
is listed as reasonably anticipated to be a human carcinogen
based on inhalation studies in laboratory animals that showed it
causes adrenal gland and lung tumors.
Diazoaminobenzene is a chemical used as an intermediate in the
production of dyes and to promote adhesion of natural rubber to
steel. Diazoaminobenzene is listed as reasonably anticipated
to be a human carcinogen based on evidence that it is metabolized
to benzene, a known human carcinogen, and because it
causes genetic damage in laboratory animals.
Nitrobenzene is a chemical used mainly in the production of other
industrial chemicals. It is listed as reasonably anticipated
to be a human carcinogen because inhalation studies of this
compound produced cancer in experimental animals.
1-Amino-2, 4-dibromoanthraquinone is a vat dye that is used in
the textile industry. It is listed as reasonably anticipated
to be a human carcinogen based on evidence that it causes
cancer in experimental animals.
4,4-Thiodianiline has been used as an intermediate in the
preparation of several kinds of dyes. It is listed as reasonably
anticipated to be a human carcinogen based on evidence that
it causes cancer in experimental animals.
Nitromethane is used in specialized fuels, explosives, and in the
synthesis of pharmaceuticals and agricultural chemicals. It is listed
as reasonably anticipated to be a human carcinogen based
on evidence that it causes cancer in experimental animals.
The Report on Carcinogens, Eleventh Edition, is prepared by the
National Toxicology Program, an interagency group coordinated by
the U.S. Department of Health and Human Services. The
full cancer report is available at the NTP website
The National Toxicology Program is located at the National Institute
of Environmental Health Sciences (NIEHS) in Research Triangle Park,
NC. Part of the National Institutes of Health, NIEHS looks at factors
in the environment that may be harmful to human health.